Viz.ai Collaborates With Johns Hopkins on Brain Injury Trial Patient Enrollment

Viz.ai is collaborating with BIOS Clinical Trials Coordinating Center (BIOS CTTC) at Johns Hopkins University, to expedite patient enrollment for the National Institutes of Health (NIH) funded Biomarker and Edema Attenuation in IntraCerebral Hemorrhage (BEACH) study.

BEACH research teams will have access to Viz.ai’s clinical trial acceleration platform, Viz™ RECRUIT software, which has demonstrated a 3X acceleration in clinical trial enrollment. Viz.ai’s cloud-based technology broadens the recruitment funnel in both size and diversity by identifying patients at trial-eligible hospitals. Viz RECRUIT identifies trial-eligible patients by scanning patient images in real-time, allowing for around-the-clock automatic identification of potential study subjects with notifications sent to research teams.

“By incorporating Viz RECRUIT software into the BEACH trial, we’re enabling more patients with intracerebral hemorrhage to get access to novel treatments like MW189,” said Dr Daniel Hanley, Co-PI of the BEACH trial at Johns Hopkins University. “Success for the development of novel treatments like this is dependent upon increased enrollment in clinical trials, which in turn opens the door for larger trials of MW189 in acute CNS injury and age-related dementias.”

The BEACH trial is studying the safety and tolerability of MW189, a small molecule, developed by Co-PI, Dr Linda Van Eldik from the University of Kentucky. It selectively attenuates injury- and disease-induced proinflammatory cytokine overproduction in patients with intracerebral hemorrhage (ICH). A key design element is the early identification and treatment of eligible and consented participants in the first day of presentation. There is currently no approved treatment for ICH, a condition that results in high rates of mortality and long-term disability.

Viz RECRUIT will help automatically identify patients with suspected ICH, with trial inclusion volumetric assessment criteria between 10mL and 60mL. It will also notify members of the research and BIOS CTCC teams of trial candidates via Viz.ai’s HIPAA-compliant web- and phone-based app that facilitates image viewing, communication and coordination.

“Clinical trial enrollment is often a bottleneck when it comes to developing novel therapies,” said Jayme Strauss, chief clinical officer at Viz.ai. “Viz RECRUIT software is designed to speed up clinical trial enrollment and promote diversity in clinical trials by identifying more eligible participants. Together, with Johns Hopkins, we have an exciting opportunity to increase access to the BEACH trial and help to enhance neurologic recovery and outcomes for patients.”