Siemens Healthineers Expands Molecular Imaging Platform with Biograph Trinion.X PET/CT

The new, FDA-cleared Biograph Trinion.X PET/CT scanner from Siemens Healthineers is making its U.S. debut at RSNA, after bring introduced globally earlier this fall. As demand for PET/CT grows in oncology, cardiology and neurology, the Biograph Trinion.X delivers the ultra-high performance and scalability needed to support the next wave of clinical and research growth.

“Molecular Imaging is experiencing a renaissance,” said Abby Weldon, marketing and sales operations, Molecular Imaging, Siemens Healthineers North America. “Volumes are increasing across the board, mainly driven by advances in radiopharmaceuticals, emerging therapies and expanding clinical indications. The Trinion.X was designed to meet that momentum.”

Extended Coverage and Higher Sensitivity

Sharing many features with its parent system the Biograph Trinion, the Biograph Trinion.X adds two axial field of view (aFOV) configurations – 36 cm and 48 cm – to the platform’s original 18 cm and 24 cm options. By adding detector rings, facilities can scale to a longer aFOV to support higher sensitivity and extended coverage.

At 48 cm, the Trinion.X fills an important market gap between standard PET/CT systems and whole-body scanners, offering a longer range of coverage with lower investment and infrastructure requirements of a whole-body system.

“This highlights how the Biograph Trinion platform was engineered for built-in upgradeability. With an upgrade to Biograph Trinion.X, our customers get to keep the same gantry while avoiding the costs and challenges of new construction,” said Weldon.

Breakthrough X-Class Detector Technology

The Biograph Trinion.X introduces proprietary X-Class detector technology to the platform that delivers 197-ps time of flight (TOF) for improved image quality and lesion detectability. Faster TOF help more accurately pinpoint when photons strike the detector with greater timing resolution. “Identifying small lesions can directly influence a patient’s treatment pathway,” Weldon said. “This is especially important in areas such as prostate cancer, where PET imaging with PSMA tracers serve as a gatekeeper for theranostic therapies.”

What’s more, this technology is packed into a small footprint with a unique air-cooled design that further simplifies siting, reduces installation costs, and supports deployment in non-traditional environments, such as outpatient cardiology centers and mobile imaging units.

The system also includes new lighting features to enhance the patient experience, including updated mood lighting around the gantry and intuitive visual cues for breath-hold guidance.

Expanding Access to Advanced PET/CT

According to Weldon, several areas are driving the most significant PET/CT growth, including cardiac, urology, neurology and oncology. “PET/CT is the gatekeeper to many of today’s most promising therapies, including theranostics. Trinion.X helps ensure more clinicians are ready to care for more patients – not just for today, but for the future, too,” she said.

The Biograph Trinion.X reflects Siemens Healthineers’ broader mission: making high-end imaging capabilities accessible to more patients. “Making advanced technology more accessible has always been a priority for us,” Weldon said. “Trinion.X continues that commitment by bringing ultra-fast TOF and extended coverage to a wider range of facilities.”

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