Fujifilm and PRECIDX Cut Digital Pathology File Sizes by 85%, Paving Way for Broader Adoption

Fujifilm Healthcare Americas Corporation has partnered with PRECIDX to integrate its Synapse® Pathologysystem with the PRECIDX Optimization Platform (POP), achieving a breakthrough in digital pathology: reducing file sizes by up to 85% without compromising diagnostic quality. The collaboration addresses one of the major barriers to digital pathology adoption—high storage costs—while improving efficiency, interoperability, and access to critical diagnostic data.

Digital pathology enables faster diagnoses, improved remote access, and streamlined workflows. However, the sheer size of whole-slide images, often between 2 and 4 GB each, has made storage a serious challenge, especially for large labs generating thousands of slides daily. This data volume quickly reaches petabytes, burdening healthcare providers with excessive storage demands and costs.

The integration is designed to ease that burden. Synapse Pathology accelerates case management and delivers digital images nearly two hours faster than traditional glass slides. Meanwhile, POP reduces image file sizes by up to 85%, transfers them up to 10 times faster, and prepares the data for interoperability across systems. The combined technologies make large-scale digital pathology more scalable and affordable for hospitals, research institutions, and diagnostic labs.

“The benefits of digital pathology are numerous – including increased efficiency, speedier diagnoses and enhanced remote access,” said Dr. Mark Lloyd, Vice President of Digital Pathology at Fujifilm Healthcare Americas. “However, the high storage costs of digital slides remain one of the major challenges for providers... Our joint technology solution offers a major opportunity to make digital pathology far more feasible for health systems.”

Despite the clinical benefits, only 13% of U.S. academic medical centers and just 2% of community hospitalscurrently use digital pathology in routine primary diagnostics. Costly storage infrastructure has remained a major obstacle, but Fujifilm and PRECIDX aim to change that.

At Pathology Visions 2025 (Oct. 5–7, San Diego), Hoag Health System, one of California’s top-ranked hospitals, will present real-world clinical findings on the Fujifilm–PRECIDX solution. Their research confirmed significant reductions in image file size while maintaining diagnostic quality. Dr. David Braxton, Chief of Molecular Pathology at Hoag Family Cancer Institute, will present a live poster session on October 5 from 5–6 p.m. in the Main Hall.

“A key barrier in the wider spread adoption of digital pathology is the significant cost of storing multi-gigabyte whole slide digital images,” said Dr. John Cupp, Director of Digital Pathology at Hoag. “The POP has achieved a great milestone in addressing this concern, all while maintaining diagnostic reproducibility.”

Dr. Michael N. Brant-Zawadzki, Hoag VP and executive sponsor of its CATALiST initiative, added: “PRECIDX’s solution opens the door for transforming pathology workflows, accelerating the flow of critical information for patient care.”

“Digital pathology holds immense promise for transforming healthcare,” said Kenneth Tang, PRECIDX CEO and co-founder. “Our partnership with Fujifilm... tackles the storage cost challenge head-on and is poised to be a true gamechanger for the digital pathology industry.”